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TMPK-00858
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NKG2C/CD159c Protein, Human, Recombinant (His & Avi)
NK cell receptor
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Human
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HEK293 Cells
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As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The p... |
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TMPK-00859
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NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated
NK cell receptor
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Human
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HEK293 Cells
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As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-... |
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TMPK-01040
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NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)
NKG2C,NK cell <...
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Cynomolgus
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HEK293 Cells
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As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. |
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TMPK-01199
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NKG2C/CD159c Protein, Mouse, Recombinant (hFc)
NKG2C,KLRC2,CD159c
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Mouse
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HEK293 Cells
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As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted m... |
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TMPK-01230
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CLEC2D Protein, Human, Recombinant (hFc & Avi)
Lectin-like NK cell ...
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Human
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HEK293 Cells
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C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART). |
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TMPK-00885
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KIR2DL3 Protein, Human, Recombinant (His & Avi)
KIR2DL3,NKAT-2,NKAT2A,KIR2DS5,KIRC
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Human
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HEK293 Cells
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KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL3 Protein, Hum... |
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TMPK-00461
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KIR2DL1 Protein, Human, Recombinant (His & Avi)
CD158A,CD158Ankat1,p58.1,KIR2DL1,...
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Human
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HEK293 Cells
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KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.1 kDa and the accession ... |
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TMPK-00462
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KIR2DL1 Protein, Human, Recombinant (His & Avi), Biotinylated
CD158Ankat1,KIR221,KIR2DL1/KIR2DS5,NK<...
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Human
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HEK293 Cells
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KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.1 kDa and ... |
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TMPK-00159
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IL-15RA Protein, Human, Recombinant (His & Avi)
IL-15 R α,IL-15RA/IL-15 R α/CD215,IL-15RA,IL-15 R a...
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Human
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HEK293 Cells
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Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. |
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TMPK-00886
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KIR2DL3 Protein, Human, Recombinant (His & Avi), Biotinylated
NKAT2B,KIR-K7c,CD158b,KIR-K7b,KIR...
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Human
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HEK293 Cells
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KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL3 Protein, Hum... |
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TMPH-01586
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KIR2DL5B Protein, Human, Recombinant (His & Myc)
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Human
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E. coli
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Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.8 kDa and the accession number is Q8NHK3. |
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TMPK-00160
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IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
MGC104179,IL-15 R α,IL-15RA,IL-15 R alpha,IL-15RA/I...
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Human
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HEK293 Cells
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Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. |
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TMPK-00883
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KIR2DL2 Protein, Human, Recombinant (His & Avi)
KIR2DL2,NKAT-6,NKAT6,CD158B1,p58 ...
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Human
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HEK293 Cells
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KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL2 Protein, Human, Recombinant (His & Avi) is... |
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TMPK-00884
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KIR2DL2 Protein, Human, Recombinant (His & Avi), Biotinylated
p58 NK receptor CL-43,
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Human
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HEK293 Cells
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KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL2 Protein, Human, Recombinant (His & Avi), B... |
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TMPK-00257
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KIR3DL3 Protein, Human, Recombinant (His & Avi), Biotinylated
KIR44,KIR2DS2,KIR3DL7,KIR3DL3,CD158Z,KIRC1
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Human
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HEK293 Cells
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Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (PBMC) and decidual natural kill (NK) cells. KIR3DL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.3 kDa and the accession number is Q8N743. |
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TMPK-01278
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CD69 Protein, Cynomolgus, Recombinant (His)
CLEC2C,AIM,EA1,MLR-3,GP32,BL-A
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Cynomolgus
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HEK293 Cells
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CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits. |
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TMPK-00956
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CD161 Protein, Human, Recombinant (His)
KLRB1,NKRP1ANKR,CD161,NK...
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Human
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HEK293 Cells
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CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19.6 kDa and the accession number is Q12918-1. |
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TMPY-04040
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CLEC2D Protein, Rat, Recombinant (hFc)
C-type lectin domain family 2, member D
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Rat
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HEK293 Cells
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Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g... |
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TMPK-00955
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CD161 Protein, Human, Recombinant (His & Avi), Biotinylated
NKRP1,HNKR-P1a,NKRP1A,CD...
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Human
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HEK293 Cells
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CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.4 kDa and the accession number is Q12918-1. |
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TMPK-01277
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CD161 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Ly59,CLEC5B,NKRP1A,CD161...
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Cynomolgus
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HEK293 Cells
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CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.5 kDa and the accession number is XP_005570142.1. |
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TMPK-00256
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KIR3DL3 Protein, Human, Recombinant (His & Avi)
KIR3DL3,KIR44,KIR2DS2,KIRC1,CD158Z,KIR3DL7
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Human
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HEK293 Cells
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Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (PBMC) and decidual natural kill (NK) cells. KIR3DL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.3 kDa and the accession number is Q8N743. |
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TMPK-01276
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CD161 Protein, Cynomolgus, Recombinant (His & Avi)
HNKR-P1a,NKRP1,KLRB1,Ly59,NKRP1A<...
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Cynomolgus
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HEK293 Cells
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CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.5 kDa and the accession number is XP_005570142.1. |
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TMPK-00647
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KIR3DL2 Protein, Rhesus macaque, Recombinant (His)
KIR3DL2,NKAT-4,NKAT4,p140,CL-5,
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Rhesus
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HEK293 Cells
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KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predi... |
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TMPJ-00898
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CD72 Protein, Human, Recombinant (Trx & His)
Lyb-2,B-Cell Differentiation Antigen C...
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Human
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E. coli
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B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulat... |
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TMPK-00887
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KIR3DL2 Protein, Human, Recombinant (His & Avi)
KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,...
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Human
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HEK293 Cells
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KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred... |
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TMPK-01105
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IL-22RA1 Protein, Human, Recombinant (hFc)
IL-22R-alpha-1,CRF2-9,IL-TIF-R1,IL-22R-α-1,IL22R1,z...
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Human
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HEK293 Cells
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Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr... |
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TMPK-01071
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IL-22RA1 Protein, Mouse, Recombinant (hFc)
IL-22R α1,IL22R,zcytoR11,IL-TIF-R1,CRF2-9,...
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Mouse
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HEK293 Cells
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Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr... |
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TMPJ-00120
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NKp80/KLRF1 Protein, Human, Recombinant (His)
Lectin-like receptor F1,C
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Human
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HEK293 Cells
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Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i... |
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TMPJ-00831
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CCL3 Protein, Mouse, Recombinant (His)
LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha,LD78 alpha,chemok...
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Mouse
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E. coli
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C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra... |
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TMPK-01450
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HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...
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Human
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HEK293 Cells
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Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
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TMPK-01456
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HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...
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Human
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HEK293 Cells
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Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
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TMPK-01451
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HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...
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Human
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HEK293 Cells
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Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
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